Science and health

THC was asked who is more sensitive. The simple answer fell apart again

Earlier research often pointed to greater THC sensitivity in women. A new experiment with 44 participants, published on 29 October in Neuropsychopharmacology, disturbed that tidy picture: men using cannabis no more than four days a week reported stronger intoxication and several unpleasant effects than some comparison groups. Researchers compared different cannabis strengths with placebo, accounting for sex and use frequency. “Men are more sensitive” is no sound replacement conclusion: the sample was small and some differences emerged in exploratory analyses.

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Primary sources

UCLA Department of MedicineSex- and frequency-dependent acute pharmacokinetic and pharmacodynamic effects of smoked cannabis: a randomized controlled trialOpen source ↗

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